Ecological effects of the feeding and construction activities of the Eurasian beaver (Castor fiber) in Scotland: Implications for reintroduction.

Beavers have been described as a “keystone species” and “ecosystem engineers”, and in this dual role have great potential to physically modify their environment through tree-felling, foraging and construction activities. The resultant change in habitat heterogeneity can affect the flora and fauna that share the habitat with them. There has been recent interest in reintroducing the Eurasian beaver to the United Kingdom after an absence of over 400 years. To date, no research (aside from this thesis) has focussed on beaver ecology and behaviour in Scotland. This study has investigated the ecological effects of a small number of beavers in two enclosed but semi-natural Scottish sites at Bamff in Perthshire. The research conducted over a three-year period, with particular emphasis on the effects of tree-felling, foraging and construction activities. Trees were felled for both dietary and construction purposes, with felling rates being influenced by habitat availability, quality and the degree of habitat modification required. Highest rates were evident during the initial colonisation period of marginal sites (c. >300 trees / beaver / calendar year), and lowest rates in later years of occupation of more optimal sites (c. 55 – 70 trees / beaver / calendar year). Preferences were generally for willow and aspen trees, with conifers almost entirely avoided, and smaller trees preferred over larger ones. Proximity of trees to waterbodies was also an important factor, with nearer trees favoured, and generally most felling occurred within 50 m of water. Such behaviour followed the principles of optimal central place foraging. These preferences were less predictable however when intense construction activity was undertaken, with larger trees preferred and generic preferences for deciduous trees apparently invalid. In such cases, close proximity to the construction site was of prime importance. Increased cover of herbaceous plant species was observed in beaver-created canopy gaps in riparian woodland, whilst macrophyte diversity within waterbodies increased slightly in areas of herbaceous grazing. The diversity of terrestrial ground invertebrates was highest in areas of heavy tree-felling, and invertebrate richness and abundance was greatest in areas of herbaceous grazing under an intact tree-canopy. Furthermore, the abundance, diversity and richness of macroinvertebrate communities were increased by beaver-generated woody debris in ponds and streams. Overall, 30% of all macroinvertebrate species collected were found only in beaver-affected areas, due to the refugia and food supply provided by beaver dams, caches and lodges, as well as hydrological effects of these structures. These results are discussed with reference to future plans to return the beaver to Scotland. The habitat usage and modification of riparian ecosystems in northern Britain is likely to be similar to that found in this study, and the results are believed to be relevant, applicable and transferable to many areas of Scotland.Scottish Natural Heritage (CASE studentship

Coccidiomycosis infection of the patella mimicking a neoplasm - two case reports.

BackgroundCoccidioidomycosis is an endemic fungal infection in the southwestern of United States. Most infections are asymptomatic or manifest with mild respiratory complaints. Rare cases may cause extrapulmonary or disseminated disease. We report two cases of knee involvement that presented as isolated lytic lesions of the patella mimicking neoplasms.Case presentationThe first case, a 27 year-old immunocompetent male had progressive left anterior knee pain for four months. The second case was a 78 year-old male had left anterior knee pain for three months. Both of them had visited general physicians without conclusive diagnosis. A low attenuation lytic lesion in the patella was demonstrated on their image studies, and the initial radiologist's interpretation was suggestive of a primary bony neoplasm. The patients were referred for orthopaedic oncology consultation. The first case had a past episode of pulmonary coccioidomycosis 2 years prior, while the second case had no previous coccioidal infection history but lived in an endemic area, the central valley of California. Surgical biopsy was performed in both cases due to diagnostic uncertainty. Final pathologic examination revealed large thick walled spherules filled with endospores establishing the final diagnosis of extrapulmonary coccidioidomycosis.ConclusionsThough history and laboratory findings are supportive, definitive diagnosis still depends on growth in culture or endospores identified on histology. We suggest that orthopaedic surgeons and radiologists keep in mind that chronic fungal infections can mimic osseous neoplasm by imaging

A COTS-Style Acquisition Strategy for Human Exploration Beyond LEO

The Evolvable Mars Campaign presents a long term strategy for NASA's Journey to Mars within a capability driven framework. By comparing each element to a set of criteria, this paper reviews the potential of acquiring those capabilities using a strategy similar to the Commercial Orbital Transportation Services program. The paper presents the criteria, assesses the elements against those criteria, and then discusses the suitability of each element to being developed using this acquisition strategy. Throughout the campaign, certain capabilities are well suited to being developed in this manner while others are not. This assessment is a snapshot in time, and should be revisited as the campaign and/or commercial capabilities change. This paper will explore each of these elements in the campaign and discuss how the COTS development andacquisition strategy could or could not be applied to those elements. This assessment will be based on theservices or functionality required in the campaign, and will use the best practices discussed above to create acase for or against a COTS-style acquisition strategy for each given element

Improving language mapping in clinical fMRI through assessment of grammar.

IntroductionBrain surgery in the language dominant hemisphere remains challenging due to unintended post-surgical language deficits, despite using pre-surgical functional magnetic resonance (fMRI) and intraoperative cortical stimulation. Moreover, patients are often recommended not to undergo surgery if the accompanying risk to language appears to be too high. While standard fMRI language mapping protocols may have relatively good predictive value at the group level, they remain sub-optimal on an individual level. The standard tests used typically assess lexico-semantic aspects of language, and they do not accurately reflect the complexity of language either in comprehension or production at the sentence level. Among patients who had left hemisphere language dominance we assessed which tests are best at activating language areas in the brain.MethodWe compared grammar tests (items testing word order in actives and passives, wh-subject and object questions, relativized subject and object clauses and past tense marking) with standard tests (object naming, auditory and visual responsive naming), using pre-operative fMRI. Twenty-five surgical candidates (13 females) participated in this study. Sixteen patients presented with a brain tumor, and nine with epilepsy. All participants underwent two pre-operative fMRI protocols: one including CYCLE-N grammar tests (items testing word order in actives and passives, wh-subject and object questions, relativized subject and object clauses and past tense marking); and a second one with standard fMRI tests (object naming, auditory and visual responsive naming). fMRI activations during performance in both protocols were compared at the group level, as well as in individual candidates.ResultsThe grammar tests generated more volume of activation in the left hemisphere (left/right angular gyrus, right anterior/posterior superior temporal gyrus) and identified additional language regions not shown by the standard tests (e.g., left anterior/posterior supramarginal gyrus). The standard tests produced more activation in left BA 47. Ten participants had more robust activations in the left hemisphere in the grammar tests and two in the standard tests. The grammar tests also elicited substantial activations in the right hemisphere and thus turned out to be superior at identifying both right and left hemisphere contribution to language processing.ConclusionThe grammar tests may be an important addition to the standard pre-operative fMRI testing

A Tale of Two Narrow-Line Regions: Ionization, Kinematics, and Spectral Energy Distributions for a Local Pair of Merging Obscured Active Galaxies

We explore the gas ionization and kinematics, as well as the optical--IR spectral energy distributions for UGC 11185, a nearby pair of merging galaxies hosting obscured active galactic nuclei (AGNs), also known as SDSS J181611.72+423941.6 and J181609.37+423923.0 (J1816NE and J1816SW, $z \approx 0.04$). Due to the wide separation between these interacting galaxies ($\sim 23$ kpc), observations of these objects provide a rare glimpse of the concurrent growth of supermassive black holes at an early merger stage. We use BPT line diagnostics to show that the full extent of the narrow line emission in both galaxies is photoionized by an AGN and confirm the existence of a 10-kpc-scale ionization cone in J1816NE, while in J1816SW the AGN narrow-line region is much more compact (1--2 kpc) and relatively undisturbed. Our observations also reveal the presence of ionized gas that nearly spans the entire distance between the galaxies which is likely in a merger-induced tidal stream. In addition, we carry out a spectral analysis of the X-ray emission using data from {\em XMM-Newton}. These galaxies represent a useful pair to explore how the [\ion{O}{3}] luminosity of an AGN is dependent on the size of the region used to explore the extended emission. Given the growing evidence for AGN "flickering" over short timescales, we speculate that the appearances and impact of these AGNs may change multiple times over the course of the galaxy merger, which is especially important given that these objects are likely the progenitors of the types of systems commonly classified as "dual AGNs."Comment: 15 pages, 10 figures, accepted by the Astrophysical Journa

Hexabromocyclododecanes (HBCDDs) in surface soils from coastal cities in North China:correlation between diastereoisomer profiles and industrial activities

Hexabromocyclododecane (HBCDD) is a brominated flame retardant with a wide range of industrial applications, although little is known about its patterns of spatial distribution in soils in relation to industrial emissions. This study has undertaken a large-scale investigation around an industrialized coastal area of China, exploring the concentrations, spatial distribution and diastereoisomer profiles of HBCDD in 188 surface soils from 21 coastal cities in North China. The detection frequency was 100% and concentrations of total HBCDD in the surface soils ranged from 0.123 to 363 ng g−1 and averaged 7.20 ng g−1, showing its ubiquitous existence at low levels. The spatial distribution of HBCDD exhibited a correlation with the location of known manufacturing facilities in Weifang, suggesting the production of HBCDD as major emission source. Diastereoisomer profiles varied in different cities. Diastereoisomer compositions in soils were compared with emissions from HBCDD industrial activities, and correlations were found between them, which has the potential for source identification. Although the contemporary concentrations of HBCDD in soils from the study were relatively low, HBCDD-containing products (expanded/extruded polystyrene insulation boards) would be a potential source after its service life, and attention needs to be paid to prioritizing large-scale waste management efforts

Status of the Combustion Devices Injector Technology Program at the NASA MSFC

To support the NASA Space Exploration Mission, an in-house program called Combustion Devices Injector Technology (CDIT) is being conducted at the NASA Marshall Space Flight Center (MSFC) for the fiscal year 2005. CDIT is focused on developing combustor technology and analysis tools to improve reliability and durability of upper-stage and in-space liquid propellant rocket engines. The three areas of focus include injector/chamber thermal compatibility, ignition, and combustion stability. In the compatibility and ignition areas, small-scale single- and multi-element hardware experiments will be conducted to demonstrate advanced technological concepts as well as to provide experimental data for validation of computational analysis tools. In addition, advanced analysis tools will be developed to eventually include 3-dimensional and multi- element effects and improve capability and validity to analyze heat transfer and ignition in large, multi-element injectors

An assessment of the impacts of pesticide use on the environment and health of rice farmers in Sierra Leone

One of the biggest challenges faced by Sierra Leonean farmers is pest control. Birds, rodents, insects, crustaceans and other organisms can drastically reduce yields. In order to prevent these organisms from destroying their crop, farmers use pesticides. However there are reports that these chemicals are being misused and such misuse is having a negative impact on the environment and the health of the farmers. This research study aimed to investigate the use of pesticides in rice fields and its potential effects on the environment and on the farmers of Sierra Leone. Five hundred farmers and one hundred health workers across the country were interviewed. Fifty focus group discussions were also completed. Field observations were also undertaken to see how farmers apply pesticides to their farms and the possible threats these methods have on human health and the environment. It is clear that a wide range of pesticides are used by rice farmers in Sierra Leone with 60% of the pesticides used entering the country illegally. Most farmers have no knowledge about the safe handling of pesticides as 71% of them have never received any form of training. The pesticides kill both target and non-target organisms some of which enter the food chain. Cases of health problems such as nausea, respiratory disorders and blurred vision investigated in this research are significantly higher among farmers who use pesticides than those who do not use pesticides. Cases of pesticide intoxication are not investigated by health workers but results obtained from interviews with them also indicated that cases of pesticides related symptoms are significantly higher in environments where pesticides are used than those in which pesticides are not used

A Prospective Evaluation of Opioid Utilization After Upper-Extremity Surgical Procedures: Identifying Consumption Patterns and Determining Prescribing Guidelines.

BACKGROUND: Although adequate management of postoperative pain with oral analgesics is an important aspect of surgical procedures, inadvertent overprescribing can lead to excess availability of opioids in the community for potential diversion. The purpose of our study was to prospectively evaluate opioid consumption following outpatient upper-extremity surgical procedures to determine opioid utilization patterns and to develop prescribing guidelines. METHODS: All patients undergoing outpatient upper-extremity surgical procedures over a consecutive 6-month period had the following prospective data collected: patient demographic characteristics, surgical details, anesthesia type, and opioid prescription and consumption patterns. Analysis of variance and post hoc comparisons were performed using t tests, with the p value for multiple pairwise tests adjusted by the Bonferroni correction. RESULTS: A total of 1,416 patients with a mean age of 56 years (range, 18 to 93 years) were included in the study. Surgeons prescribed a mean total of 24 pills, and patients reported consuming a mean total of 8.1 pills, resulting in a utilization rate of 34%. Patients undergoing soft-tissue procedures reported requiring fewer opioids (5.1 pills for 2.2 days) compared with fracture surgical procedures (13.0 pills for 4.5 days) or joint procedures (14.5 pills for 5.0 days) (p \u3c 0.001). Patients who underwent wrist surgical procedures required a mean number of 7.5 pills for 3.1 days and those who underwent hand surgical procedures required a mean number of 7.7 pills for 2.9 days, compared with patients who underwent forearm or elbow surgical procedures (11.1 pills) and those who underwent upper arm or shoulder surgical procedures (22.0 pills) (p \u3c 0.01). Procedure type, anatomic location, anesthesia type, age, and type of insurance were also all significantly associated with reported opioid consumption (p \u3c 0.001). CONCLUSIONS: In this large, prospective evaluation of postoperative opioid consumption, we found that patients are being prescribed approximately 3 times greater opioid medications than needed following upper-extremity surgical procedures. We have provided general prescribing guidelines, and we recommend that surgeons carefully examine their patients\u27 opioid utilization and consider customizing their opioid prescriptions on the basis of anatomic location and procedure type to prescribe the optimal amount of opioids while avoiding dissemination of excess opioids